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Image Search Results
Journal: Breast Cancer Research and Treatment
Article Title: Study of breast cancer incidence in patients of lymphangioleiomyomatosis
doi: 10.1007/s10549-016-3737-8
Figure Lengend Snippet: Positivity for mTORC1 signaling and metastatic markers in breast tumors of LAM patients. a Results of phospho-Ser235/236-ribosomal protein S6 (pS6) staining in two available breast tumors. Heterogeneity (i.e., positive and negative tumor cells in case #1) and positive cells with a spindle phenotype (case #2, right panels , depicted in insets ) can be observed ( arrows mark magnified regions). b Results of the analysis of the metastatic markers (FSCN1, ID1, and SOX9) in both cases. Heterogeneity (particularly in case #1) and spindle-like phenotypes (particularly in case #2) can be observed ( arrows mark magnified regions)
Article Snippet: The antibodies used in this study were anti-ERα (#IR151, Dako),
Techniques: Staining
Journal: American Journal of Translational Research
Article Title: Fascin-1 is released from proximal tubular cells in response to calcineurin inhibitors (CNIs) and correlates with isometric vacuolization in kidney transplanted patients
doi:
Figure Lengend Snippet: Urinary levels of fascin-1 are higher in kidney transplanted patients showing isometric vacuolization of tubular cells. Urinary fascin-1 (A), serum creatinine (B), proteinuria (C) and urinary KIM-1 (D) levels were analyzed in healthy volunteers, non-transplanted chronic kidney disease (CKD) patients and kidney transplanted patients presenting or not isometric vacuolization (IV) of tubular cells. Fascin-1 and KIM-1 levels were assessed using ELISA assays and the results were normalized with urinary creatinine levels. Each sample was tested twice (variation coefficient < 10%) and interplate controls were used. Data were analyzed using Kruskal-Wallis test and Dunn’s contrasts (*, P < 0.05). Fascin-1 levels in urine were significantly higher in kidney transplanted patients showing isometric vacuolization of tubular cells (A).
Article Snippet: Plasma and urine levels of fascin-1 and KIM-1 were determined with commercially available
Techniques: Enzyme-linked Immunosorbent Assay
Journal: American Journal of Translational Research
Article Title: Fascin-1 is released from proximal tubular cells in response to calcineurin inhibitors (CNIs) and correlates with isometric vacuolization in kidney transplanted patients
doi:
Figure Lengend Snippet: An increase in urinary fascin-1 levels precedes kidney dysfunction in lung transplanted patients. The graphs show the levels of fascin-1 in serial urine samples and the corresponding serum creatinine levels in lung transplanted patients 1 (A), 2 (B), 3 (C), 4 (D). Fascin-1 levels in urine were assessed using an ELISA assay and the results were normalized with urinary creatinine levels. Each sample was tested twice (variation coefficient < 10%) and interplate controls were used. Patients 2, 3 and 4 showed an increase of urinary fascin-1 levels preceding a loss of kidney function (B, C and D, respectively). Levels of creatinine serum above 1.5 mg/ml were considered altered kidney function. Tp: Transplantation.
Article Snippet: Plasma and urine levels of fascin-1 and KIM-1 were determined with commercially available
Techniques: Enzyme-linked Immunosorbent Assay, Transplantation Assay